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SEQNEXT-HLA FOR THE ANALYSIS OF YOUR
HLA NEXT GENERATION SEQUENCING DATA

NO CLOUD - STAY IN CONTROL OF YOUR DATA

SEQNEXT-HLA

SEQNEXT-HLA is a powerful and user-friendly application for the analysis of HLA sequence based typing data from all common Next Generation Sequencing platforms and kits. All IMGT HLA database versions are available for download and import. For result calculation intron sequences can be regarded to exclude null alleles, moreover the phasing can be checked.

Warnings for coverages and background can be shown up. New alleles are called as well. The result can be displayed in maximum, 1 field or 2 field resolution and as NMPD code. All result data can be transferred to laboratory internal LIM Systems and / or issued as personalised patient reports.

  • HIGHLIGHTS

    • Compatible with data from all common Next Generation Sequencing platforms and kits
    • Easy setup of individual target regions (ROIs) based on the IMGT HLA database
    • Analysis of fastq- or fastq.gz-files
    • Efficient standards for mapping, alignment, quality and allele calling
    • Configurable settings for allele calling
    • Analysis of complete loci (exon as well as intron data)
    • Detection / exclusion of null alleles based on intron sequences
    • Phasing check to remove ambiguities
    • Detection of new alleles

     

    • Display of results in different resolutions (1 field, 2-field, and max. resolution) and as NMDP code
    • Detailed summary of coverages and quality as well as information about "unused reads"
    • Warnings for low quality, low coverage, no base calling and dropouts
    • Configurable warnings for coverages and background as well as splice site mutations
    • Detailed HLA report for individual patients / orders
    • Data import (LISTENMASTER) / export (TALKMASTER) from / to any LIM System

     
  • Compatible with data from all common Next Generation Sequencing platforms and kits
  • Easy setup of individual target regions (ROIs) based on the IMGT HLA database
  • Analysis of fastq- or fastq.gz-files
  • Efficient standards for mapping, alignment, quality and allele calling
  • Configurable settings for allele calling
  • Analysis of complete loci (exon as well as intron data)
  • Detection / exclusion of null alleles based on intron sequences
  • Phasing check to remove ambiguities
  • Detection of new alleles
  • Display of results in different resolutions (1 field, 2-field, and max. resolution) and as NMDP code
  • Detailed summary of coverages and quality as well as information about "unused reads"
  • Warnings for low quality, low coverage, no base calling and dropouts
  • Configurable warnings for coverages and background as well as splice site mutations
  • Detailed HLA report for individual patients / orders
  • Data import (LISTENMASTER) / export (TALKMASTER) from / to any LIM System