PARTNERS OF JSI medical systems

JSI medical systems closely interacts with many important companies in the field of genetics, mainly sequencing platform manufacturers and enrichment/capture kit producers.

Roche offers Target Enrichment Probes, which could be developed independently, as well as in collaboration with Roche Sequencing Solutions scientists, by researchers around the world.

SEQNEXT is recommended for the data analysis. Therefore pre-defined sge-files are available for selected Roche SeqCap EZ panels for an easy import in SEQNEXT. These files are generated by JSI medical systems and validated by Roche and contain all necessary information, such as regions of interest and settings for mutation analysis including CNV detection. These SeqCap EZ panels have been defined using hg38 as a reference and depending on the type of mutations you are looking for (somatic or germline), you can download the corresponding file from here.

For the analysis of customized Roche Target Enrichment Probes, please contact our support.

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Protrans offers kits for HLA sequence based typing. The Protrans Sequencing System is designed to reach a maximum level of allele-specific sequencing and in turn the lowest number of ambiguities. With the separation of the DNA with specific primer Mixes in two separate Haplotypes ensures the recognition of both alleles in nearly all cases.

SEQHLA is recommended for the data analysis. Predefined AmpModules and SeqPrimers for Protrans HLA SBT analysis can be easily imported in the SEQHLA installation by importing the ProtransKits file.

Devyser offers diagnostic kits for complex DNA testing within oncology, reproductive health and hereditary diseases. Their products are used to guide targeted cancer therapies, to enable rapid prenatal diagnostics, as well as in a wide array of genetic tests. JSI developed a customized software plug-in that is compatible with all Devyser products, including BRCA, CFTR, Thalassemia, FH kits for NGS.

Pre-defined files are available for import in SEQNEXT. These contain all settings, such as regions of interest and validated analysis settings for mutation analysis including CNV detection.

Ulf Klangby, CEO and co-founder of Devyser, says, “Being able to offer our NGS kits to users of JSI’s software platform is a fantastic opportunity for us. JSI’s reputation of being at the forefront of bio-informatic platform development is completely aligned with our own philosophy of meeting the needs of the routine diagnostic lab, in this case those with full analytic capacity in-house.”

Joachim Strub, CEO of JSI medical systems, comments, “We are excited to enable a robust NGS solution together with Devyser. This will empower our customers and future users of the JSI platform to maintain full control of their analytical processes and results using the latest NGS technology.”

Download press release from November 2016.

NimaGen offers EasySeq NGS Targeted Capture kits for BRCA1/BRCA2 and for Hereditary Breast and Ovararian Cancer (HBOC). Using sequence capturing with single molecule Molecular Inversion Probes (smMIP), followed by a barcoding Amplification step, the system enables sequencing of the targeted regions in a very simple, fast and robust workflow, resulting in coverage with double probe tiling and independent reading of both strands.

SEQNEXT is recommended for the analysis of EasySeq NGS Targeted Capture Kits.
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Multiplicom MASTR Assays in combination with contemporary massive parallel sequencing technology allows high throughput and cost-effective sequencing for both research and diagnostic purposes.

Within SEQNEXT you can easily import the bed-files from all existing MASTR assays and build your regions of interest automatically in a matter of seconds. To obtain these bed-files, please send an e-mail to Multiplicom customer service specifying the assay and SEQNEXT as software.

By collaborating with experts from Interactive Biosoftware, we have been able to develop a link between SEQNEXT, SEQPATIENT and Alamut Visual.

SEQNEXT, SEQPATIENT and Alamut Visual are now automatically connected: any variant found by SEQNEXT, SEQPATIENT can be directly visualized and interpreted within Alamut Visual.